 |
||
|---|---|---|
| 【ProductName】 |
SIAH1 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K114642P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q8IUQ4 |
|
| 【Gene ID】 |
6477 |
|
| 【Application】 |
Blocking Peptide of K114642P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson‘s disease， the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants， some encoding different isoforms and others that have not been fully characterized.