 |
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|---|---|---|
| 【ProductName】 |
EZH1 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107561P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q92800 |
|
| 【Gene ID】 |
2145 |
|
| 【Application】 |
Blocking Peptide of K107561P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex， which methylates ’Lys-27’ of histone H3， leading to transcriptional repression of the affected target gene. Able to mono-， di- and trimethylate ’Lys-27’ of histone H3 to form H3K27me1， H3K27me2 and H3K27me3， respectively. Required for embryonic stem cell derivation and self-renewal， suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes， it is less abundant in embryonic stem cells， has weak methyltransferase activity and plays a less critical role in forming H3K27me3， which is required for embryonic stem cell identity and proper differentiation.