 |
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|---|---|---|
| 【ProductName】 |
CD14 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K101533P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P08571 |
|
| 【Gene ID】 |
929 |
|
| 【Application】 |
Blocking Peptide of K101533P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
Coreceptor for bacterial lipopolysaccharide. In concert with LBP， binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex， thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88， TIRAP and TRAF6， leading to NF-kappa-B activation， cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides， these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.