 |
||
|---|---|---|
| 【ProductName】 |
ITGA2B Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K106413P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P08514 |
|
| 【Gene ID】 |
3674 |
|
| 【Application】 |
Blocking Peptide of K106413P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
Integrin alpha-IIb/beta-3 is a receptor for fibronectin， fibrinogen， plasminogen， prothrombin， thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.