 |
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|---|---|---|
| 【ProductName】 |
TERF1 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107057P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P54274 |
|
| 【Gene ID】 |
7013 |
|
| 【Application】 |
Blocking Peptide of K107057P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Binds the telomeric double-stranded 5’-TTAGGG-3’ repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5’-TTAGGG-3’ repeats added by telomerase and protects chromosome ends; without its protective activity， telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.