 |
||
|---|---|---|
| 【ProductName】 |
PARP Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107421P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P09874 |
|
| 【Gene ID】 |
142 |
|
| 【Application】 |
Blocking Peptide of K107421P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
This gene encodes a chromatin-associated enzyme， poly(ADP-ribosyl)transferase， which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation， proliferation， and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition， this enzyme may be the site of mutation in Fanconi anemia， and may participate in the pathophysiology of type I diabetes.