 |
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|---|---|---|
| 【ProductName】 |
TNFRSF4 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107600P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P43489 |
|
| 【Gene ID】 |
7293 |
|
| 【Application】 |
Blocking Peptide of K107600P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL， and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response， as well as in T cell-dependent B cell proliferation and differentiation.