 |
||
|---|---|---|
| 【ProductName】 |
FGF4 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107658P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P08620 |
|
| 【Gene ID】 |
2249 |
|
| 【Application】 |
Blocking Peptide of K107658P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
||
Background：
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development， cell growth， morphogenesis， tissue repair， tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3， another oncogenic growth factor， are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.