 |
||
|---|---|---|
| 【ProductName】 |
NALP4 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107691P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q96MN2 |
|
| 【Gene ID】 |
147945 |
|
| 【Application】 |
Blocking Peptide of K107691P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1， and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B， suggesting that it operates at a point of convergence in these two cytokine signaling pathways.