Product Specification
 |
||
|---|---|---|
| 【ProductName】 |
GPR31 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107791P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
O00270 |
|
| 【Gene ID】 |
2853 |
|
| 【Application】 |
Blocking Peptide of K107791P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
||
Background：
High-affinity receptor for 12-(S)-hydroxy-5，8，10，14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells， and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix， which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1)， MEK， and NF-kappa-B.