Product Specification
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|---|---|---|
| 【ProductName】 |
NFATC2IP Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K108447P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q8NCF5 |
|
| 【Gene ID】 |
84901 |
|
| 【Application】 |
Blocking Peptide of K108447P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
In T-helper 2 (Th2) cells， regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes， including IL3， IL4， IL5 and IL13， but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 ’Arg-3’-methylation and facilitates subsequent histone acetylation at the IL4 locus， thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.