 |
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|---|---|---|
| 【ProductName】 |
PA2G4 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K108558P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q9UQ80 |
|
| 【Gene ID】 |
5036 |
|
| 【Application】 |
Blocking Peptide of K108558P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters， probably by recruiting histone acetylase activity. Binds RNA. Associates with 28S， 18S and 5.8S mature rRNAs， several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs. Regulates cell proliferation， differentiation， and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation.