 |
||
|---|---|---|
| 【ProductName】 |
EIF2S1 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K108663P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P05198 |
|
| 【Gene ID】 |
1965 |
|
| 【Application】 |
Blocking Peptide of K108663P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
||
Background：
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit， followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation， the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.