【ProductName】 |
TMEM106A Antibody Blocking Peptide |
|
---|---|---|
【Cat NO.】 |
K109436P-Ag |
|
【Source】 |
Synthetic |
|
【Storage】 |
Store at -20℃,2 years.Avoid freeze/thaw cycles. |
|
【Appearance】 |
Lyophilized powder |
|
【Swiss Prot】 |
Q96A25 |
|
【Gene ID】 |
113277 |
|
【Application】 |
Blocking Peptide of K109436P Antibody |
|
【Purification】 |
HPLC |
|
【Activity】 |
Not tested |
|
【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide. May play a role in inhibition of proliferation and migration.