 |
||
|---|---|---|
| 【ProductName】 |
NUS1 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K109913P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q96E22 |
|
| 【Gene ID】 |
116150 |
|
| 【Application】 |
Blocking Peptide of K109913P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
With DHDDS， forms the dehydrodolichyl diphosphate synthase (DDS) complex， an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity， i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP)， a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394， PubMed:25066056， PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2， thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B， a neural and cardiovascular regulator.