 |
||
|---|---|---|
| 【ProductName】 |
CBX6 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K109939P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
O95503 |
|
| 【Gene ID】 |
23466 |
|
| 【Application】 |
Blocking Peptide of K109939P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
Component of a Polycomb group (PcG) multiprotein PRC1-like complex， a complex class required to maintain the transcriptionally repressive state of many genes， including Hox genes， throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’， rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity).