【ProductName】 |
GRK2 Antibody Blocking Peptide |
|
---|---|---|
【Cat NO.】 |
K109974P-Ag |
|
【Source】 |
Synthetic |
|
【Storage】 |
Store at -20℃,2 years.Avoid freeze/thaw cycles. |
|
【Appearance】 |
Lyophilized powder |
|
【Swiss Prot】 |
P25098 |
|
【Gene ID】 |
156 |
|
【Application】 |
Blocking Peptide of K109974P Antibody |
|
【Purification】 |
HPLC |
|
【Activity】 |
Not tested |
|
【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.