 |
||
|---|---|---|
| 【ProductName】 |
IFT57 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K110258P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q9NWB7 |
|
| 【Gene ID】 |
55081 |
|
| 【Application】 |
Blocking Peptide of K110258P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling， cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1， leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5’-AAAGACATG-3’ present in the promoter of caspase genes such as CASP1， CASP8 and CASP10， suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.