 |
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|---|---|---|
| 【ProductName】 |
SCN9A Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K110412P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q15858 |
|
| 【Gene ID】 |
6335 |
|
| 【Application】 |
Blocking Peptide of K110412P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane， the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient (PubMed:7720699， PubMed:17167479， PubMed:25240195， PubMed:26680203， PubMed:15385606， PubMed:16988069， PubMed:17145499， PubMed:19369487， PubMed:24311784). It is a tetrodotoxin-sensitive Na+ channel isoform (PubMed:7720699). Plays a role in pain mechanisms， especially in the development of inflammatory pain (PubMed:17167479， PubMed:17145499， PubMed:19369487， PubMed:24311784).