【ProductName】 |
DHRS2 Antibody Blocking Peptide |
|
---|---|---|
【Cat NO.】 |
K110462P-Ag |
|
【Source】 |
Synthetic |
|
【Storage】 |
Store at -20℃,2 years.Avoid freeze/thaw cycles. |
|
【Appearance】 |
Lyophilized powder |
|
【Swiss Prot】 |
Q13268 |
|
【Gene ID】 |
10202 |
|
【Application】 |
Blocking Peptide of K110462P Antibody |
|
【Purification】 |
HPLC |
|
【Activity】 |
Not tested |
|
【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.