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Product Specification
【ProductName】

DHRS2 Antibody Blocking Peptide

【Cat NO.】

K110462P-Ag

【Source】

Synthetic

【Storage】

Store at -20℃,2 years.Avoid freeze/thaw cycles.

【Appearance】

Lyophilized powder

【Swiss Prot】

Q13268

【Gene ID】

10202

【Application】

Blocking Peptide of K110462P Antibody

【Purification】

HPLC

【Activity】

Not tested

【Note】

Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging.

Background:

Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.