下载
Product Specification
【ProductName】

CEBPB Antibody Blocking Peptide

【Cat NO.】

K110634P-Ag

【Source】

Synthetic

【Storage】

Store at -20℃,2 years.Avoid freeze/thaw cycles.

【Appearance】

Lyophilized powder

【Swiss Prot】

P17676

【Gene ID】

1051

【Application】

Blocking Peptide of K110634P Antibody

【Purification】

HPLC

【Activity】

Not tested

【Note】

Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging.

Background:

Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:1741402, PubMed:9374525, PubMed:12048245, PubMed:18647749). Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5’-T[TG]NNGNAA[TG]-3’. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipocytes but has an antiproliferative effect on T-cells by repressing MYC expression, facilitating differentiation along the T-helper 2 lineage. Binds to regulatory regions of several acute-phase and cytokines genes and plays a role in the regulation of acute-phase reaction and inflammation. Plays also a role in intracellular bacteria killing (By similarity). During adipogenesis,