 |
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|---|---|---|
| 【ProductName】 |
BCAP31 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K111474P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P51572 |
|
| 【Gene ID】 |
10134 |
|
| 【Application】 |
Blocking Peptide of K111474P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Functions as a chaperone protein (PubMed:9396746， PubMed:18287538). Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:9396746， PubMed:18287538). Plays a role in the export of secreted proteins in the ER， the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:9396746， PubMed:18287538). Also serves as a cargo receptor for the export of transmembrane proteins (By similarity). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed:31206022). In response to ER stress， delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed:31206022). May be involved in CASP8-mediated apoptosis (PubMed:10958671).