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Product Specification
【ProductName】

RAPGEF1 Antibody Blocking Peptide

【Cat NO.】

K111587P-Ag

【Source】

Synthetic

【Storage】

Store at -20℃,2 years.Avoid freeze/thaw cycles.

【Appearance】

Lyophilized powder

【Swiss Prot】

Q13905

【Gene ID】

2889

【Application】

Blocking Peptide of K111587P Antibody

【Purification】

HPLC

【Activity】

Not tested

【Note】

Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging.

Background:

Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.