 |
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|---|---|---|
| 【ProductName】 |
MAP4K4 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K112144P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
O95819 |
|
| 【Gene ID】 |
9448 |
|
| 【Application】 |
Blocking Peptide of K112144P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1， MAP2K4/MKK4， and MAP2K7/MKK7， which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade， and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.