 |
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|---|---|---|
| 【ProductName】 |
FMN2 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K112776P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q9NZ56 |
|
| 【Gene ID】 |
56776 |
|
| 【Application】 |
Blocking Peptide of K112776P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization (PubMed:22330775， PubMed:21730168).Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2 (PubMed:22330775， PubMed:21730168).Involved in intracellular vesicle transport along actin fibers， providing a novel link between actin cytoskeleton dynamics and intracellular transport (By similarity).Required for asymmetric spindle positioning， asymmetric oocyte division and polar body extrusion during female germ cell meiosis (By similarity).Plays a role in responses to DNA damage， cellular stress and hypoxia by protecting CDKN1A against degradation， and thereby plays a role in stress-induced cell cycle arrest (PubMed:23375502).Also acts in the nucleus: together with SPIRE1 and SPIRE2， promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (PubMed:26287480).Protects cel