 |
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|---|---|---|
| 【ProductName】 |
STIMATE Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K113510P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q86TL2 |
|
| 【Gene ID】 |
375346 |
|
| 【Application】 |
Blocking Peptide of K113510P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Acts as a regulator of store-operated Ca2+ entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM)， called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679， PubMed:26644574).SOCE is a Ca2+ influx following depletion of intracellular Ca2+ stores (PubMed:26322679).Acts by interacting with STIM1， promoting STIM1 conformational switch (PubMed:26322679).Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574).Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).