 |
||
|---|---|---|
| 【ProductName】 |
DROSHA Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K114361P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q9NRR4 |
|
| 【Gene ID】 |
29102 |
|
| 【Application】 |
Blocking Peptide of K114361P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex， which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus， yielding the precursor miRNA (pre-miRNA)， which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene， canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq， Sep 2016]