 |
||
|---|---|---|
| 【ProductName】 |
ApoE Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K115093P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20°C. Avoid freeze / thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P02649 |
|
| 【Gene ID】 |
348 |
|
| 【Application】 |
Blocking Peptide of K115093P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor， and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia， or type III hyperlipoproteinemia (HLP III)， in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.