下载
Anti-CD163(APC) Monoclonal antibody - Cy5
Cat: K010038M - Cy5
Summary:
【Product name】:Anti-CD163(APC) Monoclonal antibody - Cy5 【Source】:Mouse
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9332 【Swiss Prot】:Q86VB7
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Glycoprotein preparation from hairy cell leukemia spleen
【Storage】:Store at 2-8℃. Avoid light.
Background:
CD163, also known as M130, is a membrane glycoprotein which belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity (PMID: 12570164).
Verified picture: