Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody - SAlexa Fluor 640
Cat: K010047P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6195 | 【Swiss Prot】：Q15418 |
| 【Tested applications】：ELISA,IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human p90RSK around the phosphorylation site of Thr573 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
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