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Anti-GSDMD Polyclonal Antibody
Cat: K010048P
Summary:
【Product name】:Anti-GSDMD Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:79792 【Swiss Prot】:P57764
【Observed】:53kDa
【Tested applications】:WB,IF,ELISA,FCM
【Recommended dilution】:WB 1:2000-10000. IF 1:50-500.
【Immunogen】:Recombinant protein of human GSDMD
【Public Immunogen Range】:135-484aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Verified picture:
Western blot analysis with GSDMD antibody diluted at 1:5000;Lane: A431 Jurkat.
Immunofluorescence analysis of HeLa using GSDMD antibody diluted at 1:200.