Anti-GSDMD Polyclonal Antibody - SAlexa Fluor 594
Cat: K010048P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-GSDMD Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79792 | 【Swiss Prot】：P57764 |
| 【Observed】：53kDa | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human GSDMD | |
| 【Public Immunogen Range】：135-484aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
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