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Anti-GSDMD Polyclonal Antibody - SAlexa Fluor 647
Cat: K010048P - SAlexa Fluor 647
Summary:
【Product name】:Anti-GSDMD Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:79792 【Swiss Prot】:P57764
【Observed】:53kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human GSDMD
【Public Immunogen Range】:135-484aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
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