Anti-CD3(PE) Monoclonal Antibody - SAlexa Fluor 555
Cat: K010049M - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-CD3(PE) Monoclonal Antibody - SAlexa Fluor 555 | 【Source】：Rat |
| 【Isotype】：IgG2b，κ | 【Purification】：Affinity purification |
| 【Gene ID】：12501 | 【Swiss Prot】：P22646 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：γδTCR-positive T-T hybridoma D1 | |
| 【Storage】：Store at 2-8℃. Avoid exposure to light. | |
Background:
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
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