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Anti-LRRC25 Polyclonal Antibody - SAlexa Fluor 680
Cat: K112410P - SAlexa Fluor 680
Summary:
【Product name】:Anti-LRRC25 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:126364 【Swiss Prot】:Q8N386
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human LRRC25
【Public Immunogen Range】:1-101aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164).Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.
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