Anti-TNF Polyclonal Antibody
Cat: K112501P
Summary:
| 【Product name】：Anti-TNF Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7124 | 【Swiss Prot】：P01375 |
| 【Observed】：35kDa | |
| 【Tested applications】：IF,IHC | |
| 【Recommended dilution】：IHC 1:25-100. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TNF | |
| 【Public Immunogen Range】：1-301aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Verified picture:
Immunohistochemistry of paraffin-embedded human testis cancer with TNF antibody diluted at 1:50.