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Anti-NDE1 Polyclonal Antibody - SAlexa Fluor 750
Cat: K112522P - SAlexa Fluor 750
Summary:
【Product name】:Anti-NDE1 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:54820 【Swiss Prot】:Q9NXR1
【Observed】:46kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:2000-5000. IHC 1:25-100.
【Immunogen】:Recombinant protein of human NDE1
【Public Immunogen Range】:1-336aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.
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