下载
Anti-Ki67 Polyclonal Antibody - SAlexa Fluor 488
Cat: K010075P - SAlexa Fluor 488
Summary:
【Product name】:Anti-Ki67 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:17345 【Swiss Prot】:E9PVX6
【Observed】:358kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of mouse Ki67
【Public Immunogen Range】:1231-1330/2938aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Verified picture: