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Anti-DNAJC7 Polyclonal Antibody - SAlexa Fluor 488
Cat: K112601P - SAlexa Fluor 488
Summary:
【Product name】:Anti-DNAJC7 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:7266 【Swiss Prot】:Q99615
【Observed】:62kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human DNAJC7
【Public Immunogen Range】:136-485aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity).
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