Anti-HECTD3 Polyclonal Antibody
Cat: K112614P
Summary:
| 【Product name】：Anti-HECTD3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79654 | 【Swiss Prot】：Q5T447 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human HECTD3 | |
| 【Public Immunogen Range】：200-550aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).
Verified picture:
Immunohistochemistry of paraffin-embedded human colorectal cancer with HECTD3 antibody diluted at 1:100.