Anti-PDZD8 Polyclonal Antibody
Cat: K112697P
Summary:
| 【Product name】：Anti-PDZD8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：118987 | 【Swiss Prot】：Q8NEN9 |
| 【Species reactivity】：Human;Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：Recombinant protein of human PDZD8 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544). PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca2+ transfer (PubMed:29097544). In neurons, involved in the regulation of dendritic Ca2+ dynamics by regulating mitochondrial Ca2+ uptake in neurons (PubMed:29097544). Plays an indirect role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). May inhibit herpes simplex virus 1 infection at an early stage (PubMed:21549406).
Verified picture:
Immunohistochemistry of paraffin-embedded human renal cancer with PDZD8 antibody diluted at 1:50.