Anti-WISP1 Polyclonal Antibody
Cat: K010084P
Summary:
| 【Product name】：Anti-WISP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：8840 | 【Swiss Prot】：O95388 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：ELISA,IHC,WB | |
| 【Immunogen】：Recombinant protein of human WISP1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
WISP1( Wnt-induced secreted protein 1), also known as CCN4, is a secreted, matricellular protein allocated to the CCN protein family. The CCN protein family consists of six, modular structured, secreted proteins ( Cyr61, CTGF, Nov, WISP1, WISP2, WISP3 ). WISP1 may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. WISP1 is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. Its expression is associated with proliferation, cytoprotection, as well as extracellular matrix production. 18166-1-AP antibody detects the 40-45 kDa protein in SDS-PAGE.
Verified picture:
Western blot analysis with WISP1 antibody diluted at 1:2000;Lane: COLO 320 HEK293.
Immunohistochemistry of paraffin-embedded human stomach cancer with WISP1 antibody diluted at 1:200.