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Anti-KIF20B Polyclonal Antibody
Cat: K112927P
Summary:
【Product name】:Anti-KIF20B Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:9585 【Swiss Prot】:Q96Q89
【Species reactivity】:Human
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of human KIF20B
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Plus-end-directed motor enzyme that is required for completion of cytokinesis;Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth ;Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression
Verified picture:
Immunohistochemistry of paraffin-embedded Human prostate cancer with KIF20B antibody diluted at 1:50.