Anti-ITGAL Polyclonal Antibody
Cat: K112967P
Summary:
| 【Product name】：Anti-ITGAL Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3683 | 【Swiss Prot】：P20701 |
| 【Species reactivity】：Human;Mouse | |
| 【Tested applications】：WB;IHC | |
| 【Immunogen】：Recombinant protein of human ITGAL | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with ITGAL antibody diluted at 1:3000;Lane: HMC1.
Immunohistochemistry of paraffin-embedded human esophageal cancer with ITGAL antibody diluted at 1:50.