Anti-UBE3C Polyclonal Antibody - HRP
Cat: K112989P - HRP
Summary:
| 【Product name】：Anti-UBE3C Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9690 | 【Swiss Prot】：Q15386 |
| 【Species reactivity】：Human;Mouse | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human UBE3C | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
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