Anti-CCDC22 Polyclonal Antibody - SAlexa Fluor 532
Cat: K113007P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-CCDC22 Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：28952 | 【Swiss Prot】：O60826 |
| 【Species reactivity】：Human;Mouse;Rat | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human CCDC22 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10.
Verified picture: