Anti-RGS2 Polyclonal Antibody - SAlexa Fluor 488
Cat: K113046P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-RGS2 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5997 | 【Swiss Prot】：P41220 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RGS2 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).
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