Anti-SELENOT Polyclonal Antibody
Cat: K113158P
Summary:
| 【Product name】：Anti-SELENOT Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：51714 | 【Swiss Prot】：P62341 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：WB,IHC | |
| 【Immunogen】：A synthetic peptide of human SELENOT | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Selenoprotein with thioredoxin reductase-like oxidoreductase activity (By similarity).Protects dopaminergic neurons against oxidative stress ans cell death (PubMed:26866473).Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion (By similarity).Plays a role in fibroblast anchorage and redox regulation (By similarity).In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation (By similarity).In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PACAP-induced insulin secretion (By similarity).
Verified picture:
Immunohistochemistry of paraffin-embedded human colorectal cancer with SELENOT antibody diluted at 1:50.
Western blot analysis with SELENOT antibody diluted at 1:3000;Lane: U-251MG,HEL,HMC1,THP-1,A549,U-87MG,293T.