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Anti-BTK Polyclonal Antibody
Cat: K113219P
Summary:
【Product name】:Anti-BTK Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:695 【Swiss Prot】:Q06187
【Species reactivity】:Human;Mouse
【Tested applications】:WB
【Immunogen】:Recombinant protein of human BTK
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with BTK antibody diluted at 1:2000;Lane: 293T,HeLa,U937,Raji,K-562,L-02.