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Anti-CAPN3 Polyclonal Antibody
Cat: K113267P
Summary:
【Product name】:Anti-CAPN3 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:825 【Swiss Prot】:P20807
【Species reactivity】:Human;Mouse;Rat
【Tested applications】:WB
【Immunogen】:Recombinant protein of human CAPN3
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Verified picture:
Western blot analysis with CAPN3 antibody diluted at 1:2000;Lane: NIH3T3,Mouse skeletal muscle.